Enantioselective α-amination enabled by a BINAM-derived phase-transfer catalyst
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چکیده
منابع مشابه
Enantioselective α-amination enabled by a BINAM-derived phase-transfer catalyst† †Electronic supplementary information (ESI) available: Procedures and characterization data. CCDC 1025135. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02494j Click here for additional data file. Click here for additional data file.
Chiral anion phase-transfer of aryldiazonium cations was utilized to achieve highly enantioselective α-amination of carbonyl compounds. A broad scope of indanone- and benzosuberone-derived substrates was amenable to this strategy. Critical to obtaining high levels of enantioselectivity was the use of BINAM-derived phosphoric acids. The utility of this transformation was demonstrated through fac...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2015
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c4sc02494j